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1

Targeting HER2 for the Treatment of Breast Cancer

Rimawi, Mothaffar F., Schiff, Rachel, Osborne, C. Kent

Journal:

Annual Review of Medicine

Year:

2015

Language:

english

File:

PDF, 449 KB

english, 2015

2

β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib

Catherine Huang, Catherine C Park, Susan G Hilsenbeck, Robin Ward, Mothaffar F Rimawi, Yen-chao Wang, Jiang Shou, Mina J Bissell, C Kent Osborne, Rachel Schiff

Journal:

Breast Cancer Research

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

3

Crosstalk between the Estrogen Receptor and the HER Tyrosine Kinase Receptor Family: Molecular Mechanism and Clinical Implications for Endocrine Therapy Resistance

Arpino, Grazia, Wiechmann, Lisa, Osborne, C. Kent, Schiff, Rachel

Journal:

Endocrine Reviews

Year:

2008

Language:

english

File:

PDF, 266 KB

english, 2008

4

The changing role of ER in endocrine resistance

Nardone, Agostina, De Angelis, Carmine, Trivedi, Meghana V., Osborne, C. Kent, Schiff, Rachel

Journal:

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

5

Trastuzumab resistant HER2+ breast cancer cells retain sensitivity to poly (ADP-ribose) polymerase (PARP) inhibition.

Wielgos, Monica E, Zhang, Zhuo, Rajbhandari, Rajani, Cooper, Tiffiny S, Zeng, Ling, Forero, Andres, Esteva, Francisco J, Osborne, C. Kent, Schiff, Rachel, LoBuglio, Albert F, Nozell, Susan E., Yang, E

Journal:

Molecular Cancer Therapeutics

Year:

2018

Language:

english

File:

PDF, 1.75 MB

english, 2018

6

Development of Acneiform Rash Does Not Predict Response to Lapatinib Treatment in Patients with Breast Cancer

Parma, Jennifer, Pavlick, Anne, Schiff, Rachel, Osborne, C. Kent, Chang, Jenny C., Rimawi, Mothaffar, Trivedi, Meghana V.

Journal:

Pharmacotherapy

Year:

2013

Language:

english

File:

PDF, 43 KB

english, 2013

7

De-escalation of treatment in HER2-positive breast cancer: Determinants of response and mechanisms of resistance

Veeraraghavan, Jamunarani, De Angelis, Carmine, Reis-Filho, Jorge S., Pascual, Tomás, Prat, Aleix, Rimawi, Mothaffar F., Osborne, C. Kent, Schiff, Rachel

Journal:

Year:

2017

Language:

english

File:

PDF, 747 KB

english, 2017

8

Endocrine responsiveness: Understanding how progesterone receptor can be used to select endocrine therapy

C. Kent Osborne, Rachel Schiff, Grazia Arpino, Adrian Susan Lee, V.G. Hilsenbeck

Journal:

Year:

2005

Language:

english

File:

PDF, 168 KB

english, 2005

9

Upregulation of PKC-δ contributes to antiestrogen resistance in mammary tumor cells

Reddy, Kaladhar B, Nabha, Sanaa M, Glaros, Selina, Hong, Meng, Lykkesfeldt, Anne E, Schiff, Rachel, Osborne, Kent

Journal:

Year:

2005

Language:

english

File:

PDF, 260 KB

english, 2005

10

The growth hormone receptor antagonist pegvisomant blocks both mammary gland development and MCF-7 breast cancer xenograft growth

Jana Divisova, Isere Kuiatse, ZaWaunyka Lazard, Heidi Weiss, Franzanne Vreeland, Darryl L. Hadsell, Rachel Schiff, C. Kent Osborne, Adrian V. Lee

Journal:

Breast Cancer Research and Treatment

Year:

2006

Language:

english

File:

PDF, 904 KB

english, 2006

11

Endocrinology and hormone therapy in breast cancer: New insight into estrogen receptor-α function and its implication for endocrine therapy resistance in breast cancer

Rachel Schiff, C Kent Osborne

Journal:

Breast Cancer Research

Year:

2005

Language:

english

File:

PDF, 697 KB

english, 2005

12

Therapeutic potential of the dual EGFR/HER2

Morrison, Gladys, Fu, Xiaoyong, Shea, Martin, Nanda, Sarmistha, Giuliano, Mario, Wang, Tao, Klinowska, Teresa, Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel

Journal:

Breast Cancer Research and Treatment

Year:

2014

Language:

english

File:

PDF, 1.74 MB

english, 2014

13

Aromatase inhibitors: Future directions

C. Kent Osborne, Rachel Schiff

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 93 KB

english, 2005

14

Biology and therapeutic potential of PI3K signaling in ER+/HER2-negative breast cancer

Fu, Xiaoyong, Osborne, C. Kent, Schiff, Rachel

Journal:

Year:

2013

Language:

english

File:

PDF, 1.06 MB

english, 2013

15

Growth factor receptor cross-talk with estrogen receptor as a mechanism for tamoxifen resistance in breast cancer

C.Kent Osborne, Rachel Schiff

Journal:

Year:

2003

Language:

english

File:

PDF, 116 KB

english, 2003

16

Dominant-Negative Nuclear Receptor Corepressor Relieves Transcriptional Inhibition of Retinoic Acid Receptor but Does Not Alter the Agonist/Antagonist Activities of the Tamoxifen-Bound Estrogen Receptor

Morrison, Ashby J., Herrera, Rafael E., Heinsohn, Ester Coronado, Schiff, Rachel, Osborne, C. Kent

Journal:

Molecular Endocrinology

Year:

2003

Language:

english

File:

PDF, 354 KB

english, 2003

17

Towards personalized treatment for early stage HER2-positive breast cancer

Goutsouliak, Kristina, Veeraraghavan, Jamunarani, Sethunath, Vidyalakshmi, De Angelis, Carmine, Osborne, C. Kent, Rimawi, Mothaffar F., Schiff, Rachel

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2019

File:

PDF, 2.43 MB

2019

18

Biological mechanisms and clinical implications of endocrine resistance in breast cancer

Mario Giuliano, Rachel Schiff, C. Kent Osborne, Meghana V. Trivedi

Journal:

Year:

2011

Language:

english

File:

PDF, 577 KB

english, 2011

19

Advanced concepts in estrogen receptor biology and breast cancer endocrine resistance: implicated role of growth factor signaling and estrogen receptor coregulators

Rachel Schiff, Suleiman A. Massarweh, Jiang Shou, Lavina Bharwani, Grazia Arpino, Mothaffar Rimawi, C. Kent Osborne

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 438 KB

english, 2005

20

Inhibition of AP-1 transcription factor causes blockade of multiple signal transduction pathways and inhibits breast cancer growth

Liu, Yongmin, Ludes-Meyers, John, Zhang, Yun, Munoz-Medellin, Debbie, Kim, Hee-Tae, Lu, Chunhua, Ge, Gouqing, Schiff, Rachel, Hilsenbeck, Susan G, Osborne, C Kent

Journal:

Year:

2002

Language:

english

File:

PDF, 383 KB

english, 2002

21

Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes

Mothaffar F. Rimawi, Priya B. Shetty, Heidi L. Weiss, Rachel Schiff, C. Kent Osborne, Gary C. Chamness, Richard M. Elledge

Journal:

Year:

2010

Language:

english

File:

PDF, 231 KB

english, 2010

22

Mechanisms of Endocrine Resistance in Breast Cancer

Osborne, C. Kent, Schiff, Rachel

Journal:

Annual Review of Medicine

Year:

2011

Language:

english

File:

PDF, 411 KB

english, 2011

23

Cyclin E1 and Rb modulation as common events at time of resistance to palbociclib in hormone receptor-positive breast cancer

Guarducci, Cristina, Bonechi, Martina, Benelli, Matteo, Biagioni, Chiara, Boccalini, Giulia, Romagnoli, Dario, Verardo, Roberto, Schiff, Rachel, Osborne, C. Kent, De Angelis, Carmine, Di Leo, Angelo,

Journal:

npj Breast Cancer

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

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